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Secretary of the Institution of Environmental Sciences ( UK) over the last five years. He is Editor of that Institution' s News Sheet and Proceedings as well as being one of the General Editors of the IES/ Wiley Environment Monograph Series. The present invention relates to Interleukin- 17 ligand and receptor family members and the discovery that IL- 17 receptor A and IL- 17 receptor E form a heteromeric receptor complex that is biologically active, and that IL- 17C activity requires the IL- 17RA- IL- 17RE heteromeric receptor complex.